The results can be coma amphetamines death. Consumer Reports staff. The researchers compared amphetaminex composition of dietary supplements labeled as containing Acacia rigidula with that of the plant diet. Piness G. Life cover, January 26, His investigator, Dorothy Goodwin, suggested that the figure given for the number of physicians specializing pills weight-control practices actually was conservative. The phrase “Speed Kills” was not just used by anti-drug define.
Using historical research that draws on new primary sources, I review the causes and course of the first, mainly iatrogenic amphetamine epidemic in the United States from the s through the s. The latest national surveys show that about 3 million Americans used amphetamine-type stimulants nonmedically in the past year, in the past week, and that to are addicted. The original amphetamine epidemic was generated by the pharmaceutical industry and medical profession as a byproduct of routine commercial drug development and competition. Searching for a decongestant and bronchodilator to substitute for ephedrine, in , biochemist Gordon Alles discovered the physiological activity of beta-phenyl-isopropylamine soon to be known as amphetamine. SKF marketed it as the Benzedrine Inhaler, a capped tube containing mg of oily amphetamine base and little else. For congestion, one was meant to inhale amphetamine vapor every hour as needed. SKF-funded Harvard psychiatrist Abraham Myerson played a particularly influential role, theorizing that amphetamine adjusted hormonal balance in the central nervous system by creating or amplifying adrenergic stimulation so as to promote activity and extra-version. Because Meyerson understood minor depression as anhedonia caused by suppression of natural drives to action, amphetamine represented an ideal depression therapy to him. The US military also supplied Benzedrine to servicemen during the war, mainly as 5-mg tablets, for routine use in aviation, as a general medical supply, and in emergency kits. Along with growth in amphetamine use for psychiatric indications, the war years also saw an explosion of amphetamine consumption for weight loss, although this medical usage was not yet approved by AMA and not advertised by SKF. Off-brand pills manufactured by smaller companies dominated this market. Past-year use in would have almost certainly been higher, because many were only occasional users.
Some popular weight-loss supplements contain a synthetic compound that is chemically similar to the drug amphetamine, according to a new study by researchers at the Food and Drug Administration. However, the FDA has yet to take action regarding the findings, leading some scientists to criticize the agency. In the new study, the FDA analyzed dietary supplements that were labeled as containing Acacia rigidula, a shrub native to Texas. Products whose labels claim to contain Acacia rigidula are commonly marketed for weight loss, supposedly by suppressing appetite and burning fat. But 9 of the 21 dietary supplements tested were found to have an unnatural compound, called beta-methylphenethylamine, which is structurally similar to amphetamine. This compound has never before been tested in people, although animal studies suggest it may behave similarly to amphetamine, and could pose a public health risk, said Dr. Pieter Cohen, an assistant professor of medicine at Harvard Medical School and a general internist at Cambridge Health Alliance in Boston, who was not involved in the study. The study was published last month in the Journal of Pharmaceutical and Biomedical Analysis, but an alert about these weight-loss products has not been issued to consumers. Consumers don’t read scientific journals to find out drug safety information, he said.